Background Early intensive insulin therapy in patients with newly diagnosed type 2 diabetes
might improve β-cell function and result in extended glycaemic remissions. We did a …

Pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs) and RIG-like helicase
(RLH) receptors, are involved in innate immune antiviral responses. Here we show that …

Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell
metabolism, growth, and proliferation. GLS is being explored as a cancer therapeutic target, …

The antitumorigenic activity of antioxidants has been presumed to arise from their ability to
squelch DNA damage and genomic instability mediated by reactive oxygen species (ROS). …

The main protease (M pro ) of SARS-CoV-2 is a key antiviral drug target. While most M pro
inhibitors have a γ-lactam glutamine surrogate at the P1 position, we recently found that …

Background Concurrent chemoradiotherapy (CCRT) has been shown to improve outcomes
for stage III–IV nasopharyngeal carcinoma (NPC) patients compared with radiotherapy (RT) …

Background: This study aimed to establish an effective prognostic nomogram with or without
plasma Epstein-Barr virus DNA (EBV DNA) for nondisseminated nasopharyngeal …

As novel “post lithium‐ion batteries,” sodium‐ion batteries/potassium‐ion batteries (SIBs/PIBs)
are emerging and show bright prospect in large‐scale energy storage applications due to …

Energy balance is maintained by a complex homeostatic system involving some signaling
pathways and “nutrient sensors” in multiple tissues and organs. Any defect associated with the …

Background The role of neoadjuvant chemotherapy (NACT) for locoregionally advanced
nasopharyngeal carcinoma (NPC) is unclear. We aimed to evaluate the feasibility and efficacy …